Functionalizing DNA nanostructures with natural cationic amino acids
نویسندگان
چکیده
منابع مشابه
Synthesis of cationic porphyrin modified amino acids.
Derivatives of amino acids bearing a porphyrin moiety on a side chain were synthesized by coupling a porphyrin to a glutamic acid side chain; the utility of these compounds was demonstrated by their use in solid-phase synthesis of a peptide bearing a cationic porphyrin and by studying its DNA-binding properties.
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Before we could understand the transport interactions between the neutral and the basic amino acids, we needed to answer four questions: 1. To what extent do diamino acids actually react with transport systems in their neutral forms? First, a,fl-diamino propionic acid, pK; = 6.7, was shown to behave in transport almost entirely as a neutral amino acid, an analogue to serine and alanine in one n...
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We have previously reported that glycine, nL-phenylalanine, and Lproline inhibit the growth of young rats when added to an adequate diet at a 5 per cent level (1). Toxicity of amino acids has been reported by other workers (2-6). We have extended these studies to a number of other amino acids and have shown differences, in some cases, between the growth-inhibiting effects of natural isomers and...
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ژورنال
عنوان ژورنال: Bioactive Materials
سال: 2021
ISSN: 2452-199X
DOI: 10.1016/j.bioactmat.2021.02.012